MGUS is an abbreviation for the medical term monoclonal gammopathy of undetermined significance. Monoclonal: This describes the abnormal antibodies in MGUS, which are clones or copies of each other. Monoclonal gammopathy of undetermined significance, also called MGUS, is a condition caused by the development of altered plasma cells.
A plasma cell is a type of white blood cell that usually produces disease-fighting antibodies. Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell dyscrasia in which plasma cells or other types of antibody-producing cells secrete a myeloma protein, i.e. an abnormal antibody, into the blood; this abnormal protein is usually found during standard laboratory blood or urine tests. Monoclonal gammopathies are conditions in which abnormal proteins are found in the blood.
mgus medical abbreviation, The most common condition linked with these abnormal proteins is monoclonal gammopathy of undetermined significance (MGUS). MGUS usually causes no symptoms. Diagnosis is often done with a lab test called protein electrophoresis. Monoclonal gammopathy of undetermined significance (MGUS) is a clinically asymptomatic premalignant clonal plasma cell or lymphoplasmacytic proliferative disorder. MGUS MGUS (monoclonal gammopathy of unknown significance) is a non-cancerous condition where the body makes an abnormal protein.
mgus medical abbreviation, Before developing active myeloma, patients pass through two earlier disease stages — monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). MGUS is the first stage of myeloma before symptoms are present. Monoclonal gammopathy of undetermined significance (MGUS) is a precancerous condition and the most common plasma cell disorder. Over time, MGUS may develop into multiple myeloma.
